Non-invasive imaging of atherosclerosis

Non-Invasive Quantitative In Vivo Imaging of Atherosclerosis

Current means of measuring disease in preclinical models of atherosclerosis include ex vivo assessment of disease tissues post-mortem and non-invasive imaging primarily of structural and anatomic features of lesions, in vivo. A non-invasive, quantitative means of imaging known biologic profiles associated with atherosclerotic disease, in vivo, would enable a robust additional understanding and ...

Non-invasive assessment of atherosclerosis

Non Invasive assessment techniques of atherosclerosis include Pulse-wave velocity at the brachial artery, Intima media thickness (IMT) in the carotid artery, Multi (64)-slice computed tomography (MSCT) for imaging of coronary lesions, Arterial pulse wave form analysis, Ankle Brachial Index (ABI) and Computed Tomography for coronary calcium. The potentially applicable screening tools have to be ...

Imaging of atherosclerosis: invasive and noninvasive techniques.

Future non-invasive imaging to detect vascular plaque instability and subclinical non-obstructive atherosclerosis

Atherosclerosis underlies the major causes of death in the Western World. Our main goal is to detect early changes of atherosclerosis and to identify subjects at highest cardiovascular risk that may aid in the development of prevention approaches and better management that will decrease cardiovascular morbidity and mortality. The new methods that are of interest include the advanced vascular ul...

Autonomous Drug-Encapsulated Nanoparticles: Towards a Novel Non-Invasive Approach to Prevent Atherosclerosis

Introduction This paper proposes the concept of autonomous drug-encapsulated nanoparticle (ADENP) as a novel non-invasive approach to prevent atherosclerosis. ADENP consists of three simple units of sensor, controller (computing), and actuator. The hardware complexity of ADENP is much lower than most of the nanorobots, while the performance is maintained by the synergism in the swarm architectu...